South Africa also recorded the highest mortality rate during the second wave between December 2020 and February 2021, at 55.4 deaths per 100,000. Eswatini and Botswana recorded rates of 39.8 and 17.7 deaths per 100,000, respectively. The lowest rate was in Mauritius, which recorded no deaths during the second wave.
“The early models which predicted how COVID-19 would lead to a massive number of cases in Africa were largely the work of institutions not from our continent. This collaboration between researchers in Africa and Europe underlines the importance of anchoring analysis on Africa’s epidemics firmly here,” said Dr. Matshidiso Moeti, WHO Regional Director for Africa and co-author. We can no longer focus our understanding of disease transmission purely on the characteristics of a virus – COVID-19 operates within a social context which has a major impact on its spread.”
As well as those with large urban populations and strong international travel links, countries with high rates of HIV were also more likely to have higher mortality rates. This may be because people with HIV often have other health conditions that put them at greater risk from COVID-19, the team suggests.
The weak link between mortality rate and the timing or severity of government-imposed restrictions on day-to-day activities is shows the impact of the wide range of application and enforcement of these restrictions across the region, making a consistent impact pattern difficult to discern. Restrictions during peaks of infection are well documented to have interrupted transmission in the region.
The findings show that the earliest recorded cases of COVID-19 were in counties where most people live in urban areas, with strong international travel links and greater testing capacity. Algeria was the first of 47 African countries to report a case, on 25 February 2020. Most countries had recorded cases by late March 2020, with Lesotho the last to report one, on 14 May 2020.
Researchers document higher deaths during the second wave, as compared to the first. The peak of infections during the second wave was also higher, with 675 deaths across the continent on 18 January 2021 compared with 323 during the first wave peak on 5 August 2020. Potential under-reporting was accounted for in the analysis.
Dr Sarah Puddicombe, NIHR’s Assistant Director for Global Health Research, said: “This study offers compelling results which challenge accepted views of epidemic preparedness and resilience in Africa. It is one of a series of important contributions that the TIBA partnership, working with governments and the WHO Regional Office has made to inform local, national and pan-African responses to the COVID-19 pandemic.”
The study, published in the journal Nature Medicine, is available to read in open access: https://www.nature.com/articles/s41591-021-01491-7
The research was supported by the UK National Institute for Health Research and the Darwin Trust of Edinburgh. It also involved researchers from the Universities of Nairobi, Ghana and Hong Kong.
For further information, please contact: Rhona Crawford, Press and PR Office, Tel: +44 131 650 2246 M: 07876391498 email: rhona.crawford@ed.ac.uk and Collins Boakye-Agyemang WHO Regional Office for Africa boakyeagyemangc@who.int Tel: + 242 06 520 65 65
